How we test
The name is a claim, so here is the claim in enough detail to be checked — including the parts we deliberately do not assert.
Two questions, two methods
Characterising a synthetic peptide means answering two separate questions, and they need separate instruments. Purity asks how much of the material in the vial is the main component rather than truncated sequences, deletion products, residual reagents or salt. Identity asks whether that main component is actually the peptide it is supposed to be.
A purity figure alone is close to meaningless. Material can be 99% one substance and still be the wrong substance — a mis-sequenced analogue, a cheaper peptide substituted upstream, or a compound that never contained what the label says. This is why every batch gets both methods, and why a certificate showing only a chromatogram should be treated as half a document.
Purity: high-performance liquid chromatography
HPLC pushes the dissolved sample through a column that separates components by how strongly they interact with the stationary phase. Peptide work uses reversed-phase chromatography, typically a C18 column with a water/acetonitrile gradient and a small amount of acid to keep the peptide protonated and the peaks sharp. Components elute at different times, a UV detector records absorbance as they pass, and the result is a trace of peaks against retention time.
Purity is reported as the area of the main peak as a percentage of total integrated peak area. A batch reported at 99.1% means the main peak accounts for 99.1% of everything the detector saw. What the number does not include is anything the detector cannot see — which is why the detection wavelength matters, and why residual water and counter-ion salt sit outside the figure entirely.
Identity: mass spectrometry
The main peak is then confirmed by mass spectrometry. The sample is ionised, the instrument measures mass-to-charge ratios, and the observed molecular mass is compared against the theoretical mass calculated from the intended sequence. A match within instrument tolerance establishes that the material is the compound it claims to be. A mismatch of a few hundred daltons is a different molecule — often a deletion sequence missing one residue, which chromatography alone can easily miss because it elutes close to the target.
What the Certificate of Analysis records
Each batch ships with its own certificate. The fields that carry weight:
| Field | What it establishes |
|---|---|
| Batch / lot number | Ties the document to the vial in front of you. Without it, the certificate describes some other material. |
| Product name and sequence | What was supposed to be made, in unambiguous form. |
| HPLC purity (%) | Main peak area as a share of total peak area. |
| Observed vs theoretical mass | Whether the main component is the intended molecule. |
| Appearance | Cake condition — collapse or discolouration indicates a lyophilisation or storage problem. |
| Date of analysis | How old the data is relative to the material. |
How to read a peptide COA walks through a certificate field by field, and spotting a fabricated COA covers what forged documents get wrong.
Independent verification, on select batches
In addition to in-house analysis, select batches are sent to an independent third-party laboratory for purity verification. The point of an outside laboratory is that it has no interest in the result: it did not synthesise the material and does not sell it.
We do not claim that every batch is independently verified. It is not true, and the unqualified version of the claim also quietly reassigns our own in-house chromatography to somebody else's laboratory. It is the most common overstatement in this industry and it is worth learning to notice.
Claims we will not make
- ISO/IEC 17025 accreditation. We do not hold it and neither does the laboratory we use. The claim is widespread and almost never carries an accreditation number — which is the only thing that would let you check it. Ask for the number and the scope.
- Testing performed in Australia. Verification is performed offshore. Our stock is held and dispatched domestically, and those are different claims that are frequently blurred together.
- Pharmaceutical or therapeutic grade. These are research chemicals. They are not therapeutic goods, not TGA-approved for human use, and not manufactured under a therapeutic goods licence.
- Dosing or administration protocols. Never, on any page. Protocol design belongs to the researcher.
Why nothing is for sale yet
Ordering opens in September 2026. Current batches are with the independent laboratory, and stock is not released until that analysis is returned — which is the entire point of the arrangement. Releasing on the strength of our own data alone and verifying afterwards would make the verification decorative.
Frequently asked questions
- Is every batch independently verified by a third party?
- No, and any supplier telling you otherwise is either overstating their programme or misattributing their own in-house chromatography to somebody else's laboratory. Every batch receives in-house HPLC and mass spectrometry and a batch-specific Certificate of Analysis. Select batches are additionally sent to an independent third-party laboratory for purity verification.
- Do you hold ISO/IEC 17025 accreditation?
- No. Neither we nor the independent laboratory we use holds ISO/IEC 17025 accreditation, and we will not claim it. The claim appears routinely across this industry and is almost never accompanied by an accreditation number, which is the only thing that would make it verifiable. If a supplier claims it, ask for the number and the scope of accreditation.
- Where is the third-party testing performed?
- Verification is performed by an independent laboratory offshore. We do not publish the laboratory's name or country, because naming a contracted lab publicly invites both impersonation of their reports and pressure on the relationship. What we will publish is the batch-specific report itself.
- What does HPLC actually establish?
- High-performance liquid chromatography separates the components of a sample and reports the relative area of each. It establishes how much of the material is the main component versus everything else, which is what a purity percentage means. It does not, on its own, establish that the main component is the peptide you ordered — that requires mass spectrometry.
- What does mass spectrometry add?
- Mass spectrometry measures the molecular mass of the main component and compares it to the theoretical mass of the intended sequence. A purity result with no mass confirmation tells you the material is 99% one thing without establishing what that thing is. Purity and identity are separate questions and need separate methods.
- Will I get the COA for my specific batch?
- Yes. Each batch has its own certificate carrying the batch number printed on the vial label. A certificate that cannot be matched to a batch number describes some other material, and is worth nothing as evidence about yours.
Launching September 2026
Ordering opens once current batches return from independent third-party purity verification. Nothing is released before that analysis is in hand.
One email at launch. Nothing else.